Sleep!
Sleep is an important part of our daily routine, we spend one-third part of our day sleeping( A Sehgal et al), but have you ever wondered why do we feel sleepy? what happens when we sleep? how is sleep regulated? What would happen if you don’t sleep for some days consecutively? Sleep is regulated by circadian rthymn, Circadian rhythms are biological processes that endogenously oscillate with a period of 24 h. It is just like a clock present inside our body but it's complicated, owing to the fact that it is synchronized by feeding patterns, light, temperature. The central circadian pacemaker is in the suprachiasmatic nucleus (It is present in the hypothalamus which is in the brain) in mammals, other cells ( Jennifer A Mohawk et al), including the cells of the Blood-Brain barrier (It is a functional separation between circulating blood and central Nervous system), have circadian rthymn driven by molecular clocks. The Blood-brain Barrier (BBB) permeability is controlle...